Androgenetic alopecia (male and female pattern balding) is by far the most common cause of hair loss amongst men and a serious problem for different women. There are three crucial components which are responsible for equally female and male balding:
1. A genetic predisposition for balding to occur.
2. Excessive presence of male hormones.
3. Aging - sufficient period for the first two factors to occur.
Together men and women produce male hormones that have a useful role to play in equally sexes; but the truth that androgens occur in much higher concentrations in men explains why male pattern baldness is more ordinary than the woman balding.
DHT the root cause of hair loss
It is metabolism of male hormones (androgen/testosterone) which is valuable cause of hair loss and male and woman pattern balding both in men and women.
The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone (testosterone) and converts it to DHT (Dihydro-testosterone). DHT is a accepted metabolite of our body.
The cause of male and lady pattern balding
A few individuals, together men and women, are genetically pre-disposed to produce more DHT than the normal individuals. It is this accumulation of DHT and its reaction on the cells in the hair follicle and root which is one of the important causes of male and woman pattern balding.
When DHT gets into the hair follicle and root, especially a region called the dermal papilla, it changes the cell’ activity and prevents required proteins, vitamins and minerals from providing nourishment looked-for to sustain life inside the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate. This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and acquire progressively slighter and finer. This practice is known because miniaturization and causes the hair to ultimately fall. DHT induced androgenetic aloepcia is responsible for 95% of every hair loss.
Blocking the synthesis of DHT at the molecular level forms the basis for the treatment of MPHL (male pattern hair loss) and FPHL (lady pattern hair loss). There are choice of accepted DHT blockers and numerous drugs which are used for medical hair restoration.
